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Some regional prescribing information and facts also notes that temazepam could be employed for premedication previous to minor medical procedures or other similar strategies 12.
Lonafarnib may possibly improve the AUC and peak focus of CYP2C19 substrates. If coadministration unavoidable, watch for adverse reactions and decrease the CYP2C19 substrate dose in accordance with its authorized merchandise labeling.
Inappropriate conduct and also other adverse behavioral outcomes happen to be claimed when making use of benzodiazepines.
Monitor for indications of respiratory depression That could be better than in any other case envisioned and reduce muscle relaxant dosage as vital.
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ceritinib will increase the stage or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
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diazepam and daridorexant both equally enhance sedation. Modify Therapy/Monitor Closely. Coadministration improves possibility of CNS despair, which may lead to additive impairment of psychomotor efficiency and lead to daytime impairment.
lumefantrine will decrease the extent or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
eslicarbazepine acetate will lower the level or result of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Coadministration of encorafenib with sensitive CYP3A4 substrates may possibly end in elevated toxicity or diminished efficacy of these brokers.
Temazepam is specially indicated just for the quick-term administration of insomnia Label, twelve. Also, these types of management is mostly predominantly connected to the symptomatic relief of transient and brief-expression sleeplessness characterized by issue read more in slipping asleep, Repeated nocturnal awakenings and/or early morning awakenings 13. Particularly, the Formal prescribing data for temazepam generally specifies the Directions issued for dispensed prescriptions with the medication need to point out especially that clients are only anticipated to use the therapy for brief periods of time - commonly 7-ten times generally speaking Label,thirteen.
triclabendazole will raise the level or outcome of diazepam by affecting hepatic enzyme CYP2C19 metabolism.
quinupristin/dalfopristin will increase the degree or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.